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05 FEB 15
Fertility Check
In cases where desired pregnancy is not achieved, as well as in cases of miscarriages, laboratory testing is necessary. The following should first be ruled out:
- The possibility of hormonal imbalance in women, which can be done through a Fertility Check-up, especially in cases of unstable or problematic menstrual cycles.
- The possibility of problems with male sperm.
If no issues arise from these tests, then the following are recommended:
Karyotype analysis in both women and men. This examination checks the number and quality of chromosomes. Genetic abnormalities in chromosomes can make natural pregnancy difficult and pose serious health risks for the child.
Testing for thrombophilia: Mutations in specific genes involved in blood clotting regulation may increase the likelihood of blood clots in the uterine vessels at the implantation site. This can make blood flow difficult or interrupted in the uterus vessels, leading to problematic embryonic development and eventual miscarriage.
A complete thrombophilia check is recommended, which includes:
- Biochemical thrombophilia testing, which checks for possible pathological conditions of the blood clotting mechanism.
- Molecular thrombophilia testing, which checks for possible genetic mutations that cause blood clots.
Testing for endometriosis: Endometriosis, where endometrial tissue develops outside the uterus, is one of the significant causes of infertility. This condition is diagnosed through laparoscopy, which is invasive. Laboratory testing can indicate the need for laparoscopic examination by detecting inflammation markers of the ovaries CA- 125 and the general inflammatory marker IL-6.
DNA testing for bacterial infections: Classical cultures recommended in fertility testing often yield falsely negative results, reaching up to 60% in some cases. However, in cases of infertility, confirmatory detection in urine for ureaplasma, mycoplasma, and chlamydia, using the sensitive DNA detection method PCR, is recommended after negative culture results.
These tests are recommended to be done gradually (to reduce costs) and under the guidance and monitoring of the responsible gynaecologist or geneticist.
No special preparation is required for these analyses.
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Cycle Disorders Assessment
The instability of a woman's cycle can originate from many causes. Blood tests will detect hormonal disorders, anaemias, and infections that can affect a woman's cycle and her fertility, often to a great extent.
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Vaginitis Examination
Vaginitis is a common inflammatory condition affecting the vagina and the broader lower genital tract of women. It can be caused by: Infections from bacteria, fungi, and viruses (which can also be sexually transmitted) Irritations from chemicals in creams, sprays, and contact with specific clothing. Vaginitis is often asymptomatic. However,
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Polycystic Ovary Syndrome (PCOS) Assessment
Polycystic Ovary Syndrome (PCOS) is one of the leading causes of infertility in women, as well as a factor in more general gynaecological issues. It affects 5-10% of women from adolescence and is the most common gynaecological disorder. It typically presents with unexpected hair growth on the chest, abdomen, and face, combined with an irregular or problematic menstrual cycle.
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Fertility Check
In cases where desired pregnancy is not achieved, as well as in cases of miscarriages, laboratory testing is necessary. The following should first be ruled out: The possibility of hormonal imbalance in women, which can be done through a Fertility Check-up, especially in cases of unstable or problematic menstrual cycles. The possibility of problems with male sperm. If no issues arise from these tests,
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Osteoporosis
Bones are a "living organism" that constantly undergoes reconstruction through osteoclasts (mechanism of bone resorption) and osteoblasts (mechanism of bone synthesis). The two mechanisms are in balance, which can be disturbed for many reasons (menopause, genetic type, hormonal imbalance, poor diet, smoking, lack of exercise, etc.) and can lead to bone loss.
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Prenatal Assessment
Prenatal Assessment is an essential part of pregnancy preparation, as it provides information about the health of the mother and the baby to be born. Complete blood count: It evaluates haematological parameters such as haematocrit, white blood cells, and platelets for possible anaemias, infections,
